Submitted or In Prep

  1. Kwapis JL, Alaghband Y, Dong TN, Michael CM, Rhee D, Shu G, Dang RT, Matheos DP, Wood MA. A novel OUL updating paradigm reveals age-related impairments in memory updating. (Submitted, Neuropsychopharmacology).

  2. Kwapis JL, Alaghband Y, Lopez AJ, Long JM, Li X, Shu G, Bodinayake KK, Matheos DP, Rapp PR, Wood MA. HDAC3-mediated repression of the Nr4a family contributes to age-related impairments in long-term memory. (In Press, The Journal of Neuroscience).


Published

  1. Kwapis JL, Alaghband Y, Kramár EA, Vogel Ciernia A, López AJ, White AO, Shu G, Rhee D, Michael CM, Montellier E., Liu Y, Magnan CN, Sassone-Corsi P, Baldi P, Matheos DP, Wood MA. (2018) Epigenetic regulation of the circadian gene Per1 in the hippocampus mediates age-related changes in memory and synaptic plasticity. Nature Communications, 9, 3323. **Originally a preprint: bioRxiv: 301135

  2. Alaghband Y, Kramár E, Kwapis JL, Kim ES, Hemstedt TJ, López AJ, White AO, Al-Kachak A, Aimiuwu OV, Bodinayake KK, Oparaugo NC, Han J, Lattal KM, Wood MA. (2018). CRET in the nucleus accumbens core regulates cocaine conditioned place preference, cocaine-seeking behavior, and synaptic plasticity. The Journal of Neuroscience, 38, 9514-9526.

  3. López AJ, Jia Y, White AO, Kwapis JL, Espinoza M, Hwang P, Campbell R, Alaghband, Matheos DP, Lynch G, Wood MA. Medial habenula cholinergic signaling regulates cocaine-associated relapse-like behavior. (In Press, Addiction Biology).

  4. Shu G, Kramár EA, López AJ, Huynh G, Wood MA, Kwapis JL. (2018). Deleting HDAC3 rescues long-term memory impairments induced by disruption of the neuron-specific chromatin remodeling complex subunit BAF53b. Learning and Memory, 25: 109-114.

  5. Kwapis JL, Alaghband Y, López AJ, White AO, Campbell RR, Dang RT, Rhee D, Tran AV, Carl AE, Matheos DP, Wood MA. (2017). Context and auditory fear are differentially regulated by HDAC3 activity in the lateral and basolateral subnuclei of the amygdala. Neuropsychopharmacology, 42: 1284-1294. PMID: 27924874.

  6. Alaghband Y, Kwapis JL, López AJ, White AO, Osasumwen VA, Al-Kachak A, Bodinayake KK, Oparugo NC, Dang R, Astarabadi M, Matheos DP, Wood MA. Distinct roles for the deacetylase domain of HDAC3 in the hippocampus and medial prefrontal cortex in the formation and extinction of memory. (In Press, Neurobiology of Learning and Memory).

  7. White AO, Kramár EA, López AJ, Kwapis JL, Doan J, Saldana D, Davatolhagh MF, Alaghband Y, Blurton-Jones M, Matheos DP, Wood MA. (2016). BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens. Nature Communications, 7: 11725. PMID: 27226355.

  8. López AJ, Kramár EA, Matheos DP, Kwapis JL, White AO, Vogel-Ciernia A, Wood MA. (2016). Promoter-specific effects of DREADD modulation on synaptic plasticity and hippocampal learning. Journal of Neuroscience, 36: 3588-3599. PMID: 27013687.

  9. Kwapis JL, Wood MA. (2014). Epigenetic mechanisms in fear conditioning: Implications for treating post-traumatic stress disorder. Trends in Neurosciences, 37: 706-720. PMID: 25220045.

  10. Kwapis JL, Jarome TJ, Ferrara NC, Helmstetter FJ. (2017). Updating procedures can reorganize the neural circuit supporting a fear memory.Neuropsychopharmacology, 42: 1688-1697. PMID: 28139682.

  11. Jarome TJ, Ferrara NC, Kwapis JL, Helmstetter FJ. (2016). CaMKII regulates proteasome phosphorylation and activity and promotes memory destabilization following retrieval. (2016). Neurobiology of Learning and Memory, 128: 103-109. PMID: 26779588.

  12. Kwapis JL, Jarome TJ, Lee JL, Helmstetter FJ. (2015). The retrosplenial cortex is involved in the formation of memory for context and trace fear conditioning.Neurobiology of Learning and Memory, 123: 110-116. PMID: 26079095.

  13. Jarome TJ, Ferrara NC, Kwapis JL, Helmstetter FJ. (2015). Contextual information drives the reconsolidation-dependent updating of retrieved fear memories.Neuropsychopharmacology, 40: 3044-3052. PMID: 26062788.

  14. Kwapis JL, Jarome TJ, Helmstetter FJ. (2014). The role of the medial prefrontal cortex in trace fear extinction. Learning and Memory, 22: 39-46. PMID: 25512576.

  15. Jarome TJ, Kwapis JL, Hallengren JJ, Wilson SM, Helmstetter FJ. (2013). The ubiquitin-specific protease 14 (USP14) is a critical regulator of long-term memory formation. Learning and Memory, 21: 9-13. PMID: 24344179.

  16. Kwapis JL, Helmstetter FJ. (2014). Does PKM(zeta) maintain memory? Brain Research Bulletin, 105: 36-45. PMID: 24076105.

  17. Kwapis JL, Jarome TJ, Lee JL, Gilmartin MR, Helmstetter FJ. (2014). Extinguishing trace fear engages the retrosplenial cortex rather than the amygdala.Neurobiology of Learning and Memory, 113: 41-54. PMID: 24055593.

  18. Jarome TJ, Kwapis JL, Ruenzel WL, Helmstetter FJ. (2013). CaMKII, but not protein kinase A, regulates Rpt5 phosphorylation and proteasome activity during the formation of long-term memories. Frontiers in Behavioral Neuroscience, 7: 115. PMID: 24009566.

  19. Gilmartin MR, Kwapis JL, Helmstetter FJ. (2013). NR2A- and NR2B-containing NMDA receptors in the prelimbic medial prefrontal cortex differentially mediate trace, delay, and contextual fear conditioning. Learning and Memory, 15: 290-294. PMID: 23676200.

  20. Jarome TJ, Kwapis JL, Werner CT, Parsons RG, Gafford GM, Helmstetter FJ. (2012). The timing of multiple retrieval events can alter GluR1 phosphorylation and the requirement for protein synthesis in fear memory reconsolidation. Learning and Memory, 19: 300-306. PMID: 22723052.

  21. Kwapis JL, Jarome TJ, Gilmartin MR, Helmstetter FJ. (2012). Intra-amygdala infusion of the protein kinase Mzeta inhibitor ZIP disrupts foreground context fear memory. Neurobiology of Learning and Memory, 98: 148-153. PMID: 22659643.

  22. Gilmartin MR, Kwapis JL, Helmstetter FJ. (2012). Trace and contextual fear conditioning are impaired following unilateral microinjection of muscimol in the ventral hippocampus or amygdala, but not the prefrontal cortex. Neurobiology of Learning and Memory, 97: 452-464. PMID: 22469748.

  23. Kwapis JL, Jarome TJ, Schiff JC, Helmstetter FJ. (2011). Memory consolidation in both trace and delay fear conditioning is disrupted by intra-amygdala infusion of the protein synthesis inhibitor anisomycin. Learning and Memory, 18: 728-732. PMID: 22028394.

  24. Jarome TJ, Werner CT, Kwapis JL, Helmstetter FJ. (2011). Activity dependent protein degradation is critical for the formation and stability of fear memory in the amygdala. PLoS One, 6: e24349. PMID: 21961035.

  25. Jarome TJ, Kwapis JL, Nye SH, Helmstetter FJ. (2010). Introgression of Brown Norway chromosome 1 onto the fawn hooded hypertensive background rescues long-term fear memory deficits. Behavior Genetics, 40: 85-92. PMID: 21961035.

  26. Kwapis JL, Jarome TJ, Lonergan ME, Helmstetter FJ. (2009). Protein kinase Mzeta maintains fear memory in the amygdala but not in the hippocampus.Behavioral Neuroscience, 123: 844-850. PMID: 19634944.